20. "Genetics Of Alzheimer's Disease"

Summary: This study sheds light on the idea that Down's Syndrome, dementia, and Alzheimer's disease may have related neuropathical changes.

Key Facts:
"While there are many studies establishing the validity and reliability of clinical assessment in the distinction between Alzheimer's disease and other causes of prehensile dementia."
"This is particularly relevant to the problem presented by patients over the age of 60 when Alzheimer's neuropathological changes may be present without clinical evidence of a dementia."
"Universal development of Alzheimer's neruopathological changes in Down's syndrome and erroneously links this with a report of six cases of Down's syndrome among the 777 relatives of 30 patients with AD."
"When chromosomal abnormalities have been directy observes in AD they are indistinguishabble from those seen with aging and are not specific for AD or related to any abnormality or chromosome 21."

Whalley, L. "Genetics Of Alzheimer's Disease." JSTOR. British Medical Journal, 22 May
1982. Web. 29 Jan. 2015. <http://www.jstor.org/stable/29506546>.

17. "Study suggests sleeping drugs can increase risk of Alzheimer’s"

Summary: The Guardian online describes sleeping medications and they could be linked chemical possibility and cause of some cases of Alzheimer's. The study shows that different drugs with the chemical transmitter acetylcholine block the nervous system and could ultimately lead to permanent damage in the long term. The chemical transmitter is being studied and is thought to be directly linked to cases of Alzheimer's disease.

Key Facts:

"The sleeping medication Nytol and anti-allergy pills Benadryl and Piriton all belong to a class of drug highlighted in a warning from researchers."
"Anticholinergic drugs block a nervous system chemical transmitter called acetylcholine, which can lead to side-effects including drowsiness, blurred vision and poor memory."

"The scientists tracked the health of 3,434 men and women aged 65 and over for around seven years while monitoring their use of anticholinergic drugs. Of those, 637 developed Alzheimer’s and 160 were afflicted by other forms of dementia."

"People with Alzheimer’s disease are known to lack acetylcholine."

"Study Suggests Sleeping Drugs Can Increase Risk of Alzheimer's." The Guardian. The
Guardian, 26 Jan. 2015. Web. 31 Jan. 2015. <http://www.theguardian.com/society/2015/jan/27/sleepi ng-drugs-increased-risk-alzheimers>.

12. "Detecting Alzheimer's Disease"

Summary: Through tests of pupil dilation and cornea behavior, the authors were able to use data analysis to discover those who were probable to have Alzheimer's disease and/or dementia. By using measurements of pupils and range of motion, pupillary responses show notable differences and predict the sicknesses.

Key Facts:
"Even if the reported difference between patients with AD and normal subjects proves to be a result of non-pharmacological factors, it may still represent a potentially valuable diagnostic tool."
"Several letters suggest that our finding may have been a result of an increased permeability of the cornea in patients with probable AD. We agree that a change in permeability is one possible
mechanism."

Marx, Jeffrey, Sanjiv Kumar, Allen Thach, Tien Kiat-Winarko, Donald Frambach,
Adrian Treloar, Mandy Assin, Alastair Macdonald, Barrett Katz, Nunzio Pomara, Natraj Sitaram, L. Scinto, K. Daffner, D. Dressler, B. Ransil, D. Rentz, S. Weintraub, M. Mesulam, and H. Potter. "Detecting Alzheimer's Disease." JSTOR. American Association for the Advancement of Science, 17 Mar. 1995. Web. 31 Jan. 2015. <http://www.jstor.org/stable/2886714>.

8. "CAREGIVER BURDEN, ELDER ABUSE AND ALZHEIMER'S DISEASE: TESTING THE RELATIONSHIP"

Summary: Gainey and Payne write about Alzheimer's Disease and their studies on whether or not dementia proclaims the reasoning behind abuse of the elderly and mentally ill. The conclusion of the study was that dementia and Alzheimer's was not necessarily directly associated with misguided caregivers, but more of the fact that the mental illness and instability cause an amount of stress that then causes abuse and aggression.

Key Facts:

"Among others, those who have a drug problem and those who suffer from a mental health problem have been found to be more like to be abusive."

"The abuse group was less dependent on the caregiver group than the non-abused group was."

"The trans-generational violence explanation refers to the possibility that abusers learned how to be abusive from their parents or other role models."

"The caregiver burden explanation is traced to research on the relationship between dementia and elder abuse. Indeed, research shows that individuals living with Alzheimer's and related diseases are 2.25 times more likely than other older persons to be physically abused."

"An early explanation of this type of elder abuse was that the victim suffered from some form of impairment which made him or her dependent on an overburdened caregiver."

"Essentially, it's not the situational context that necessarily causes burden, but something else."

"What this suggests is that alternative interventions may be needed for elder abuse victims."

GAINEY, RANDY, and BRIAN PAYNE. "CAREGIVER BURDEN, ELDER ABUSE
AND ALZHEIMER'S DISEASE: TESTING THE RELATIONSHIP." JSTOR. SPAEF, 1 Jan. 2006. Web. 31 Jan. 2015. <http://www.jstor.org/stable/25790690>.

2. "Behavioral Symptoms Hit Early in Alzheimer's"

Summary: Alzforum, a website dedicated to the research of Alzheimer cures, published an article talking about behavioral systems and their presence in those with and without dementia. Issues concerning dressing ones self, holding a job, and paying bills and emotions regarding depression, anxiety, and depression all come to those with the disease, however they are obtained faster in those with dementia.

Key Facts:

"Irritability and depression are common and tend to develop in a particular order, they occur sooner in people who progress to dementia."

"According to the functional activities scale, people en route to cognitive problems struggled with daily living activities such as paying bills, shopping, and preparing meals, while people who remained cognitively normal did not. "

"Behavioral Symptoms Hit Early in Alzheimer's | ALZFORUM." Alzforum, 21 Jan.
2015. Web. 31 Jan. 2015. <http://www.alzforum.org/news/research-news/behavioral-symptoms-hit-early-alzheimers>.