Summary: Through much technical and scientific jargon, Edwardson and Morris talk about the e4 allele of apolipoporotein E and how so far in the studies of Tanzi's work it is the only for sure genetic linking factor to Alzheimer's Disease. However until disease slowing treatments are developed, there is not enough justification to test whether or not there are other genetic links with late onset Alzheimer's Diesease.
Key Facts:
"In contrast to early onset Alzheimer's disease, there is to date only one genetic factor indisputably linked with late onset forms of this disorder, and that is the e4 allele of apolipoporotein E."
"However, the statistical analysis of this work used an as yet unpublished family based association method which, though it measures relative risk for the actual families studied, does not indicate the general population risk."
Edwardson, Jim. "The Genetics of Alzheimer's Disease: The Number of Genetic Risk
Factors Associated with This Disorder Is Increasing Steadily." JSTOR. British Medical Journal, 8 Aug. 1998. Web. 31 Jan. 2015. <http://www.jstor.org/stable/25180033>.
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